====Kanto Region (カントー地方 Kantō-chihō?), introduced in Red and Green (Blue in international releases), later seen in Yellow, Gold, Silver, Crystal, FireRed, LeafGreen, HeartGold, and SoulSilver, was the first region in the Pokémon series. It is attached to the Johto region so the player can also visit it by train or jetboat in Gold, Silver, Crystal, HeartGold and SoulSilver. In these games, however, the region differs from the earlier games (which are set three years previously) in several plot and graphical points. In the games, its cities are named after colors. Two areas of the Kanto region, Saffron City and the Pokémon Stadium, are playable stages in Nintendo's popular Super Smash Bros. fighting games. In the anime, Ash travels in Kanto in the Kanto and Battle Frontier seasons. Kanto represents the actual region in Japan called Kantō, which is its namesake, and eastern Tōkai.
Kanto is home to a handful of legendary Pokémon. The most powerful is the Genetic Pokémon Mewtwo, who was created by tampering with the DNA of the Pokémon Mew, a Pokémon that is said to have the DNA of every other Pokémon in its body and is believed to be the ancestor of all Pokémon, at the mansion on Cinnabar Island. Mewtwo's genetic structure was further manipulated to transform it into a powerful and ruthless psychic until it turned on its creators and escaped to the Cerulean Cave. The remaining legendary Pokémon are Articuno, who is said to appear to doomed travelers in icy regions, Zapdos, who is found during thunderstorms, and Moltres, who is said to bring about an early spring with its arrival.====f